Antibiotics are ineffective against Human Metapneumovirus (HMPV) as it is a viral infection, not a bacterial one. Antibiotics target bacteria, and since viruses lack the structures antibiotics work on, they cannot treat HMPV. Treatment primarily focuses on relieving symptoms like fever and congestion through rest, hydration, and over-the-counter medications. In severe cases, especially in high-risk individuals, antiviral medications like ribavirin or intravenous immunoglobulin (IVIG) may be used under medical supervision. It’s essential to avoid unnecessary antibiotic use to prevent resistance. For proper care, consult a healthcare provider if symptoms worsen or persist.